Table 1.
RecT/RobT carriers and embryos tested by MaReCs
| Translocation | Patient ID | Sex | Karyotype of the parental translocation carrier | Total no. embryos tested | Breakpoint location | Type I | Type II | Type III | C* | N† |
| RecT | 34825‡ | F | 46,XX,t (1, 8)(q25;q21.2) | 9 | chr1:161500001; chr8:68850001 | 3 | 5 | 1 | 1 (1) | 2 (2) |
| 38098 | F | 46,XX,t (12, 19)(q13;q13.3) | 9 | chr12:44200001; chr19:42500001 | 4 | 3 | 2 | 2 (1) | 2 (1) | |
| 38591‡ | M | 46,XY,t (6, 12)(q22;q21) | 6 | chr6:13040; chr12:81500001 | 3 | 3 | 0 | 1 (0) | 2 (2) | |
| 38606 | M | 46,XY,t (5, 10)(p15;p11.1) | 6 | chr5:11900001; chr10:28600000 | 2 | 4 | 0 | 1 (1) | 1 (0) | |
| 38744‡,§ | F | 46,XX,t (9, 21)(q24;q22.1) | 7 | chr9:8200000; chr21:19600000 | 1 | 6 | 0 | 0 (0) | 1 (1) | |
| 38888 | M | 46,XY,t (7, 20)(p21;q13.2) | 8 | chr7:45800001; chr20:43100000 | 4 | 4 | 0 | 1 (0) | 3 (2) | |
| 39960‡ | M | 46,XY,t (7, 15)(p22,q24) | 3 | chr7:3300001; chr15:79200001 | 1 | 2 | 0 | 0 (0) | 1 (1) | |
| 40116‡ | M | 46,XY,t (16, 18)(p13.1;q11.2) | 10 | chr16:13700001; chr18:25300001 | 3 | 7 | 0 | 0 (0) | 3 (3) | |
| 41416‡ | M | 46,XY,t (7, 15)(p15;q24) | 3 | chr7:34800001; chr15:74000001 | 2 | 1 | 0 | 2 (1) | 0 (0) | |
| 41476 | M | 46,XY,t (2, 18)(q37;q22) | 5 | chr2:209400001; chr18:42100001 | 3 | 1 | 1 | 2 (2) | 1 (1) | |
| 42309 | M | 46,XY,t (3, 7)(q13.2;q34) | 8 | chr3:127000001; chr7:150700001 | 3 | 5 | 0 | 2 (2) | 1 (1) | |
| 42606 | M | 46,XY,t (5, 17)(q35;p13) | 7 | chr5:qter; chr17:10600001 | 3 | 4 | 0 | 2 (2) | 1 (1) | |
| 42723 | F | 46,XX,t (5, 16)(p13;q13) | 15 | chr5:31260001; chr16:61640001 | 9 | 5 | 1 | 5 (4) | 4 (3) | |
| RobT | 35518‡ | F | 45,XX,rob (14, 21)(q10;q10) | 4 | chr14:q10; chr21:q10 | 2 | 2 | 0 | 2 (1) | 0 (0) |
| 40135 | M | 45,XY,rob (14, 21)(q10,q10) | 5 | chr14:q10; chr21:q10 | 4 | 1 | 0 | 3 (2) | 1 (1) | |
| 41375 | M | 45,XY,rob (13, 15)(q10,q10) | 3 | chr13:q10; chr15:q10 | 2 | 1 | 0 | 0 (0) | 2 (2) | |
| Total | M: 11 | — | 108 | — | 49 | 54 | 5 | 24 (17) | 25 (21) | |
| F: 5 | ||||||||||
F, female; M, male.
*
Embryos identified as carrier. Parenthetical number indicates embryos without any chromosomal abnormality.
†
Embryos identified as noncarrier. Parenthetical number indicates embryos without any chromosomal abnormality.
‡
Cases confirmed by karyotyping with amniocentesis.
§
Live birth with normal ploidy.