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. 2016 Oct 11;2016(10):CD002142. doi: 10.1002/14651858.CD002142.pub4

4. Changes in results over time.

  Trend or interaction
1998
Trend or interaction
2005
Trend or interaction
2010 'old' methods
Trend or interaction
2010 'new' methods
and TNM changes
Age P = 0.34 P = 0.44 P = 0.32 P = 0.20
Sex P = 0.94 P = 0.92 P = 0.84 P = 0.49
Histology P = 0.75 P = 0.61 P = 0.42 P = 0.38
Stage P = 0.0003 P = 0.003 P = 0.003 P = 0.12
Nodal status P = 0.016 P = 0.02 P = 0.03 P = 0.39