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. 2016 Oct 11;2016(10):CD002142. doi: 10.1002/14651858.CD002142.pub4

EORTC 08861.

Methods 1986 to 1990 RCT
Participants 106 patients
 Stages II, III
Trial data used in subgroup analyses for sex, age, histology, stage and nodal status
Interventions Surgery + radiotherapy vs surgery alone
 RT details
 56 Gy in 28 fractions in 5.5 weeks
 Prescription technique: central axis, at the midplane
 Machine used: linac
 Average field size (cm): 15 × 10
 Clinical target volume: hilum, mediastinum
 Technique: composite plans
Outcomes Survival
Notes Unpublished trial
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Comment: unpublished trial; checks run on IPD suggest adequate sequence generation
Allocation concealment (selection bias) Low risk Comment: unpublished, insufficient information provided, but collection of IPD and correspondence with those who supplied the data reassured that data were adequate
Blinding (performance bias and detection bias) 
 All outcomes Low risk Comment: trial not blinded owing to the nature of the intervention; outcome not likely influenced by lack of blinding
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comment: individual participant data obtained and checked for all outcomes
Selective reporting (reporting bias) Low risk Comment: individual participant data obtained and checked for all outcomes
Other bias Low risk Comment: study apparently free of other sources of bias