EORTC 08861.
Methods | 1986 to 1990 RCT | |
Participants | 106 patients
Stages II, III Trial data used in subgroup analyses for sex, age, histology, stage and nodal status |
|
Interventions | Surgery + radiotherapy vs surgery alone RT details 56 Gy in 28 fractions in 5.5 weeks Prescription technique: central axis, at the midplane Machine used: linac Average field size (cm): 15 × 10 Clinical target volume: hilum, mediastinum Technique: composite plans | |
Outcomes | Survival | |
Notes | Unpublished trial | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Comment: unpublished trial; checks run on IPD suggest adequate sequence generation |
Allocation concealment (selection bias) | Low risk | Comment: unpublished, insufficient information provided, but collection of IPD and correspondence with those who supplied the data reassured that data were adequate |
Blinding (performance bias and detection bias) All outcomes | Low risk | Comment: trial not blinded owing to the nature of the intervention; outcome not likely influenced by lack of blinding |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Selective reporting (reporting bias) | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Other bias | Low risk | Comment: study apparently free of other sources of bias |