GETCB 05CB88.
Methods | 1988 to 1994 RCT |
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Participants | 539 patients
Stages I, II, III Trial data used in subgroup analyses for sex, age, stage and nodal status |
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Interventions | Surgery + radiotherapy vs surgery alone RT details 60 Gy in 24 to 30 fractions in 6 weeks Prescription technique: isocentre Machine used: Co60 and linac (majority linac) Average field size (cm): unavailable Clinical target volume: bronchial stump, hilum, mediastinum Technique: spinal cord blocks, oblique fields, lateral fields | |
Outcomes | Survival | |
Notes | Same publication as GETCB 04CB86 | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "randomly assigned by centralised telephone procedure" Comment: stated as randomised in paper; checks run on IPD suggest adequate sequence generation |
Allocation concealment (selection bias) | Low risk | Comment: randomisation by central telephone call |
Blinding (performance bias and detection bias) All outcomes | Low risk | Comment: trial not blinded owing to the nature of the intervention; outcome not likely influenced by lack of blinding |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Selective reporting (reporting bias) | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Other bias | Low risk | Comment: study apparently free of other sources of bias |