Italy 2002.
Methods | 1989 to 1997 RCT |
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Participants | 104 patients
Stage I Trial data used in subgroup analyses for age, sex, histology and stage |
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Interventions | Surgery + radiotherapy vs surgery alone RT details 50.4 Gy in 1.8 Gy/d in 5 weeks and 3 days Prescription technique: angled field technique machine used: linac Average field size (cm): unavailable Clinical target volume: bronchial stump, hilum, mediastinum Technique: unavailable | |
Outcomes | Survival | |
Notes | — | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "by chance" using computer‐generated model Comment: stated as randomised in paper; checks run on IPD suggest adequate sequence generation |
Allocation concealment (selection bias) | Low risk | Comment: computer‐generated randomisation, which was checked by an independent colleague |
Blinding (performance bias and detection bias) All outcomes | Low risk | Comment: trial not blinded owing to the nature of the intervention; outcome not likely influenced by lack of blinding |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Selective reporting (reporting bias) | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Other bias | Low risk | Comment: study apparently free of other sources of bias |