Korea 2007.
Methods | 1989 to 1998 RCT |
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Participants | 111 patients
Stages II, III Trial data used in subgroup analyses for sex, age, histology, stage and nodal status |
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Interventions | Surgery + radiotherapy vs surgery alone RT details 50.4 to 55.8 Gy in 1.8 to 2 Gy fractions, 5 times a week Prescription technique: at midplane Average field size: defined inferiorly by a point 5 cm below the carina and superiorly by the suprasternal notch Clinical target volume: tumour bed, bronchial stump, ipsilateral hilum, vascular shadows of the bilateral mediastinum Technique: combination of parallel opposed, and anterior and posterior oblique fields, or any combination chosen at the discretion of the chest radiation oncologist | |
Outcomes | Survival | |
Notes | Abstract only | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Comment: stated as randomised in paper; checks run on IPD suggest adequate sequence generation |
Allocation concealment (selection bias) | Low risk | Comment: insufficient information provided in abstract, but collection of IPD and correspondence with those who supplied the data reassured that data were adequate |
Blinding (performance bias and detection bias) All outcomes | Low risk | Comment: trial not blinded owing to the nature of the intervention; outcome not likely influenced by lack of blinding |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Selective reporting (reporting bias) | Low risk | Comment: individual participant data obtained and checked for all outcomes |
Other bias | Low risk | Comment: study apparently free of other sources of bias |