TABLE 1.

Characteristics of ILCOO studies

Study name	Country	Controls	Period of enrolment	Cases		Controls		Age range (years) in protocol
Principal investigator	(location)			n	Participation Rate* (%)	n	Participation Rate * (%)
EAGLE	Italy	Population	2002–2005	407	86.6	498	72.4	35–79
MT Landi	(Lombardy region)
ESTHER	Germany	Population	2000–2003	52	Nested case-control study	52	Nested case-control study	50–75
H Brenner	(Saarland)
LCSS	USA	Population	1992–2009	2005	85	993	80	More than 18A
D Christiani	(Boston, Massachusetts)
MLCCCS	Canada	Population	1996–1997	422	81.7	576	69.4	More than 35B
A Koushik	(Montreal area)
MLCS	USA	Population/Hospital	1998–2010	540	80	777	80	No age restrictionC
CC Harris	(Baltimore City and Eastern Shore of Maryland)
NELCS	USA	Population	2005–2008	149	61	148	46	30–74
E Duell	(New Hampshire and Vermont)
TORONTO	Canada	Population/Hospital	1997–2002	235	62	559	60	20–84
RJ Hung; J McLaughlin	(Metropolitan Toronto)
WELD	USA	Population	1984–2005	576	83	574	70.6	18–74
AG Schwartz	(Wayne, Macomb and Oakland counties)
Total				4386		4177

^*Participation Rate as mentioned in the published study protocols.

^AAge range (years) in ILCCO: (23–93).

^BAge range (years) in ILCCO: (33–75).

^CAge range (years) in ILCCO: (27–97).