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. Author manuscript; available in PMC: 2018 Sep 5.
Published in final edited form as: Mol Pharm. 2017 Aug 22;14(9):3228–3237. doi: 10.1021/acs.molpharmaceut.7b00586

Table 1.

Composition, Size, and Zeta Potential of the Self-Encapsulating PLGA Microsphere Formulationa

PLGA concentration (mg in 1
mL)
volume of inner water phase
(mL)
trehalose loading
(wt %)b
Measured CaHPO4 loading
(wt %)c
volume median diameter
(µm)
zeta potential
(mV)
50 0.1 5 2.2 ± 0.1 7.05 ± 0.31 −21.9 ± 2.1
a

Data represent mean ± SEM, n = 3.

b

Theoretical loading.

c

Theoretical loading = 5 wt %.