Table 1.

Composition, Size, and Zeta Potential of the Self-Encapsulating PLGA Microsphere Formulation^a

PLGA concentration (mg in 1 mL)	volume of inner water phase (mL)	trehalose loading (wt %)b	Measured CaHPO4 loading (wt %)c	volume median diameter (µm)	zeta potential (mV)
50	0.1	5	2.2 ± 0.1	7.05 ± 0.31	−21.9 ± 2.1

^aData represent mean ± SEM, n = 3.

^bTheoretical loading.

^cTheoretical loading = 5 wt %.