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. Author manuscript; available in PMC: 2018 Sep 5.
Published in final edited form as: Mol Pharm. 2017 Aug 22;14(9):3228–3237. doi: 10.1021/acs.molpharmaceut.7b00586

Table 2.

Active Self-healing Encapsulation of Ovalbumin (OVA) by PLGA Microspheresa

theoretical % (w/w)
loadingb
measured % (w/w)
loading
% encapsulation
efficiencyc
OVA capacity of CaHPO4 within
microspheresd,e
OVA capacity of unencapsulated
CaHPO4 geld,f
1.0 0.60 ± 0.05 56 ± 6 0.27 ± 0.03 0.21 ± 0.01
a

Encapsulation was performed using 20 mg of microspheres in 0.4 mL of a 0.5 mg/mL OVA solution. Data represent mean ± SEM, n = 3.

b

mg of total OVA in loading solution/(mg of microspheres in sample + mg of total OVA in solution).

c

Efficiency relative to the original mass of OVA in the loading solution.

d

mg OVA loaded/mg CaHPO4 gel.

e

Based upon the determined mass of CaHPO4 gel loaded within the microspheres.

f

Determined for OVA loaded onto unencapsulated CaHPO4 gel.