Table 2.
Active Self-healing Encapsulation of Ovalbumin (OVA) by PLGA Microspheresa
| theoretical % (w/w) loadingb |
measured % (w/w) loading |
% encapsulation efficiencyc |
OVA capacity of CaHPO4 within microspheresd,e |
OVA capacity of unencapsulated CaHPO4 geld,f |
|---|---|---|---|---|
| 1.0 | 0.60 ± 0.05 | 56 ± 6 | 0.27 ± 0.03 | 0.21 ± 0.01 |
Encapsulation was performed using 20 mg of microspheres in 0.4 mL of a 0.5 mg/mL OVA solution. Data represent mean ± SEM, n = 3.
mg of total OVA in loading solution/(mg of microspheres in sample + mg of total OVA in solution).
Efficiency relative to the original mass of OVA in the loading solution.
mg OVA loaded/mg CaHPO4 gel.
Based upon the determined mass of CaHPO4 gel loaded within the microspheres.
Determined for OVA loaded onto unencapsulated CaHPO4 gel.