Table 2. Cellular Compartments of Proteins Involved in BRAFi Resistance.

Top 10 GO categories (sorted by decreasing enrichment factor) representing enzymes, excluding kinases, with significantly different ATP probe uptake between naïve and resistant cell line groups (log₂ ratio differs by more than 2 standard deviations from the mean and p-value < 0.05).

GO Biological Process (Naïve)	#	GO Biological Process (Resistant)	#
mitochondrial part	22	actin filament bundle	3
mitochondrion	35	stress fiber	6
cytoplasmic part	79	actomyosin	6
intracellular organelle part	75	adherens junction	8
organelle part	75	anchoring junction	8
cytoplasm	95	actin cytoskeleton	13
intracellular organelle	98	cytosol	14
organelle	98	cytoplasmic part	18
intracellular part	111	cytoplasm	18
intracellular	113	intracellular part	29