Recovery from ischemia with VEGF and IGF treatment for middle and old age mice. a–b) Quantification of regional perfusion (a) and capillary density (b) for old mice treated with VEGF+IGF gel, VEGF-only gel, IGF-only gel and control (blank) alginate gel. c–d) Quantification of regional perfusion (c) and capillary density (d) for middle age mice treated with VEGF+IGF gel, VEGF-only gel, and control (blank) alginate gel. Values are Mean±SD, n=4–6. *p < 0.05 vs control condition, N.S. indicate no statistical significant differences between conditions.