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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Clin Plast Surg. 2017 Apr 18;44(3):535–540. doi: 10.1016/j.cps.2017.02.026
Stage of Injury Background Anxiety Background Pain Procedural Anxiety Procedural Pain
Acute Burn Ventilated #1 Midazolam infusion Morphine infusion Midazolam boluses Morphine boluses
#2 Dexmedetomidine infusion Morphine infusion Dexmedetomidine higher infusion rate Morphine boluses
#3 Antipsychotics Morphine infusion Haloperidol (very slow) boluses Morphine boluses
#4 Propofol infusion (<48 h) Morphine infusion Propofol boluses Morphine boluses
Acute Burn not ventilated Dexmedetomidine IV Scheduled Lorazepam IV or PO Morphine IV or PO Lorazepam IV/PO Morphine IV/PO or Ketamine IV
Chronic Acute Burn Scheduled lorazepam or antipsychotics (PO) Scheduled morphine or methadone Lorazepam or antipsychotics (PO) Morphine PO or Oxycodone

Fentanyl infusions could be substituted for morphine infusions.

In view of the increased incidence of delirium with benzodiazepines, minimal use of them is advocated.

IV = intravenous. PO = per oram (by mouth).