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. 2017 Sep 15;51(5):1449–1459. doi: 10.3892/ijo.2017.4126

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Copyright: © Liao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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DUSP1 regulates the ERK pathway and PTEN regulates the AKT pathway. (A and B) DUSP1 mRNA and protein levels were significantly reduced after SiDUSP1. (B) Expression of pERK was increased after SiDUSP1. (C and D) PTEN mRNA and protein levels were significantly reduced after SiPTEN. (D) Expression of pAKT was increased after SiPTEN. The changes of DUSP1 and PTEN mRNA levels were presented as fold change in comparison to the control. ^*P<0.05, ^**P<0.01, ^***P<0.001.