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. 2017 Oct 2;2017:3037876. doi: 10.1155/2017/3037876

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Copyright © 2017 Alexandra C. Sevastre-Berghian et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effects of curcumin on total (a) and peripheral (b) travelled distance and total (c) and peripheral (d) number of entries in the open field test (OFT). Total travelled distance (a) and travelled distance in the periphery (b) were significantly increased in the diazepam and curcumin group as compared to the control group (p < 0.05). Four weeks of curcumin administration in comparison to DZP treatment increased significantly the locomotor activity (zone transition number (c) and number of entries in the periphery (d)) (p < 0.05). Each group consisted of 5 rats. Results are expressed as mean ± SEM. ^∗p < 0.05 as compared with control/CUR + CMC; ^#p < 0.05 as compared with DZP + CMC.