Figure 1. Effect of resistance training on FGF-21 and irisin levels in diabetic skeletal muscles and their associations with grip strength. After 8 weeks of progressive resistance training, the levels of (A) FGF-21 and (B) irisin were measured in SOL, EDL, TA, and GAS muscles. The associations of grip strength with (C) FGF-21 and (D) FGF-21 levels in the SOL muscles were evaluated. A p value *p<0.05 was statistically significant in comparing findings between the ZLC-Con group and the ZDF-Ex group. Pearson’s correlation coefficients and p values are shown in each graph.