Table 3.

Dysfunctional high density lipoprotein (Dys-HDL) expressed as HDL inflammatory index (HII), HDL, and LDL levels at enrollment and at 48 hours by composite adverse outcome. Changes reflect 48 hour values – enrollment values. SD = standard deviation. IQR = interquartile range.

Variable	Total (N=35)	Death, Discharge to Hospice or Nursing Home (N= 18)	Discharge to Home or Rehab (N=17)	P-value*
Dysfunctional HDL (HII), median (IQR)
Enrollment HII	2.3 (1.8–3.0)	2.3 (1.8–2.7)	2.4 (1.9–3.5)	0.70
48 hour HII	2.2 (1.8–2.6)	2.4 (2.1–2.8)	2.1 (1.5–2.3)	0.09
Change in HII	0.11 (−0.47 – 0.29)	0.21 (−0.13 – 0.31)	−0.11 (−1 – 0.11)	0.025
HII Increase in first 48 hours	20/35	13/18	7/17	0.09
High Density Lipoprotein (HDL), mean in mg/dL (SD)
Enrollment HDL	29 (3.7)	28 (4.1)	31 (6.3)	0.71
48 hour HDL	18 (2.5)	16 (4.9)	19 (4.2)	0.53
Change in HDL	−11 (2.3)	−13 (3.3)	−9 (3.2)	0.31
Low Density Lipoprotein (LDL), mean in mg/dL (SD)
Enrollment LDL	48 (4.8)	53 (6.5)	41 (7.1)	0.21
48 hour LDL	52 (5.0)	48 (4.3)	56 (9.8)	0.40
Change in LDL	2 (4.1)	−6 (4.2)	13 (7.2)	0.027

^*HII parameters were analyzed using Wilcoxon rank-sum test for numerical data and Fisher’s exact test for categorical data; HDL and LDL values were analyzed using student’s t test.