Table 4.
Correlation Matrix displaying Spearman’s correlations between changes in HDL inflammatory index and changes in inflammatory cytokines and chemokines over the first 48 hours of admission. Dysfunctional high density lipoprotein (Dys-HDL) expressed as HDL inflammatory index (HII). GRO = growth related oncogene, interleukin-6 = IL-6, interferon gamma-induced protein = IP-10, MCP-1 = monocyte chemotactic protein-1, IL-10 = interleukin-10, TNF-α = tumor necrosis factor alpha, IFN-γ = interferon gamma. Significant P-values in bold.
| Change in Marker | HII | GRO | IL6 | IP10 | MCP1 | IL10 | TNF-α | IFN-γ |
|---|---|---|---|---|---|---|---|---|
| HII | 1.0000 | |||||||
|
GRO P-value |
−0.5226 0.0088 |
1.0000 | ||||||
|
IL-6 P-value |
−0.3400 0.1040 |
0.7113 0.0001 |
1.0000 | |||||
|
IP-10 P-value |
−0.2583 0.2230 |
0.1583 0.4601 |
0.4513 0.0269 |
1.0000 | ||||
|
MCP-1 P-value |
−0.6139 0.0014 |
0.4843 0.0165 |
0.6704 0.0003 |
0.5330 0.0073 |
1.0000 | |||
|
IL-10 P-value |
−0.0278 0.8973 |
0.2417 0.2551 |
0.6304 0.0010 |
0.5635 0.0041 |
0.3339 0.1108 |
1.0000 | ||
|
TNF-α P-value |
−0.2296 0.2805 |
0.1939 0.3639 |
0.5435 0.0061 |
0.8157 0.0000 |
0.4843 0.0165 |
0.6817 0.0002 |
1.0000 | |
|
IFN-γ P-value |
−0.2623 0.2156 |
0.4595 0.0239 |
0.4534 0.0261 |
0.4868 0.0158 |
0.3116 0.1382 |
0.2192 0.3034 |
0.2535 0.2319 |
1.0000 |