Table 2.
The analysis results for the ADNI data. p and q denote the numbers of SNPs and of probes surviving the P-value cut-off based on the corresponding univariate SNP-gene expression associations
| Cut- off |
(p, q) | SPC.P(γ) | aSPC.P | RV.asy | RV.perm | Mantel | dCov | aSPC.Sp | aSPC.dCor | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||
| γ = 1 | 2 | 3 | 4 | 5–8, ∞ | |||||||||
| 1 | (2483, 382) | 5.85e-02 | 3.68e-02 | 2.87e-01 | 3.00e-04 | 1.00e-04 | 8.00e-04 | 6.89e-02 | 7.17e-02 | 8.69e-02 | 5.61e-02 | 9.00e-04 | 5.00e-04 |
| 0.9 | (2274, 380) | 3.63e-02 | 4.50e-02 | 2.16e-01 | 5.00e-04 | 1.00e-04 | 8.00e-04 | 6.47e-02 | 6.37e-02 | 9.76e-02 | 4.99e-02 | 8.00e-04 | 5.00e-04 |
| 0.8 | (2069, 371) | 2.29e-02 | 2.09e-02 | 2.22e-01 | 1.00e-04 | 1.00e-04 | 8.00e-04 | 3.87e-02 | 3.86e-02 | 7.40e-02 | 2.62e-02 | 8.00e-04 | 5.00e-04 |
| 0.7 | (1871, 357) | 3.26e-02 | 8.60e-03 | 2.39e-01 | 1.00e-04 | 1.00e-04 | 7.00e-04 | 2.01e-02 | 2.05e-02 | 5.81e-02 | 1.27e-02 | 8.00e-04 | 5.00e-04 |
| 0.6 | (1647, 353) | 1.39e-02 | 4.40e-03 | 1.74e-01 | 1.00e-04 | 1.00e-04 | 9.00e-04 | 9.22e-03 | 8.90e-03 | 4.71e-02 | 6.50e-03 | 7.00e-04 | 6.00e-04 |
| 0.5 | (1435, 351) | 1.62e-02 | 2.90e-03 | 2.80e-01 | 1.00e-04 | 1.00e-04 | 6.00e-04 | 6.69e-03 | 7.70e-03 | 5.96e-02 | 3.10e-03 | 6.00e-04 | 6.00e-04 |
| 0.4 | (1228, 340) | 1.99e-02 | 8.00e-04 | 2.54e-01 | 1.00e-04 | 1.00e-04 | 9.00e-04 | 1.91e-03 | 2.30e-03 | 1.49e-02 | 1.60e-03 | 9.00e-04 | 4.00e-04 |
| 0.3 | (999, 306) | 5.95e-02 | 1.20e-03 | 4.62e-01 | 1.00e-04 | 1.00e-04 | 8.00e-04 | 1.48e-03 | 1.50e-03 | 7.30e-03 | 9.00e-04 | 8.00e-04 | 1.00e-04 |
| 0.2 | (756, 286) | 7.54e-02 | 6.00e-04 | 5.93e-01 | 1.00e-04 | 1.00e-04 | 7.00e-04 | 6.07e-04 | 2.00e-04 | 2.00e-03 | 4.00e-04 | 9.00e-04 | 4.00e-04 |
| 0.1 | (485, 245) | 2.93e-01 | 1.00e-04 | 3.34e-01 | 1.00e-04 | 1.00e-04 | 7.00e-04 | 8.29e-05 | 3.00e-04 | 4.00e-04 | 2.00e-04 | 8.00e-04 | 4.00e-04 |