. Author manuscript; available in PMC: 2018 Nov 1.

Published in final edited form as: J Pharm Sci. 2017 Jul 22;106(11):3242–3256. doi: 10.1016/j.xphs.2017.07.012

Table 2.

Differences in IU/TU, trans/cis ratios and PC, PD percentages for crofelemer samples (n=1) as determined by qCNMR.

Sample	Trans/Cis	PC%	PD%	IU/TU
Unfractionated, TO	0.69	31.16	68.84	6.76
Unfractionated, 30 Day, 25°C	0.82	34.51	65.49	4.93
Unfractionated, 30 Day, 40°C	IS^*	50.54	49.46	IS^*
10 kDa Top, TO	0.72	33.52	66.48	4.27
10 kDa Top, 30 Day, 25°C	0.72	24.88	75.12	4.87
10 kDa Top, 30 Day, 40°C	0.64	72.58	27.42	4.53
3 kDa Top, T0	0.58	23.6	76.4	3.79
3 kDa Top, 30 Day, 25°C	0.73	47.33	52.67	3.61
3 kDa Top, 30 Day, 40°C	0.77	43.02	56.98	4.27

insufficient signal