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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Apoptosis. 2017 Nov;22(11):1380–1393. doi: 10.1007/s10495-017-1409-8

Figure 5. Rac1 mediates HG-induced expression of CD36 in INS-1 832/13 cells: Protection by metformin.

Figure 5

Panel A: Quantification of the CD36 and actin bands was done by densitometric analysis and ratios were calculated over actins in the presence and absence of EHT 1864. *p < 0.05 vs 2.5mM glucose alone [n=3].

Panel B: INS-1 832/13 cells were treated with LG [2.5mM] and HG [20mM] with or without Metformin [30μM] for 24 hrs. Relative abundance of CD36 was determined by Western blotting. Actin was used as a loading control. Data are representative of three experiments.

Panel C: Quantification of the CD36 and actin bands was done by densitometry and ratios were calculated over actins in the presence and absence of metformin. *p < 0.05 vs 2.5mM glucose alone [n=3].