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KCa3.1 channel is involved in OGD-induced reduction in viability of astrocytes. Cell viability was determined using the CCK-8 assay. The values represent the fold changes of cell viability induced by OGD. Genetic deletion of the KCa3.1 channel attenuated the decrease in viability of astrocytes after 4 h OGD, compared with WT cells (n = 5). The data are expressed as means ± SEM. **p < 0.01, ***p < 0.001. WT, wild type; KO, knockout; OGD, oxygen–glucose deprivation.
