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KCa3.1 deficiency reduces infarction volume. Focal cerebral ischemia was induced by permanent middle cerebral artery occlusion (pMCAO). (A–C) Representative TTC staining of five corresponding coronal brain sections of WT and KO mouse after 3 h (A), 6 h (B) and 24 h (C) of pMCAO. (D) Quantitative analysis of infarction volume in 3, 6 and 24 h, respectively. Data are presented as means ± SEM. n = 5. *p < 0.05, compared with ischemic WT group.
