Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Signal transduction pathways by which a reduction in O2 concentration inhibits prolyl-4-hydroxylases (PHDs) and Factor Inhibiting HIF-1 (FIH), leading to HIF-1α stabilization and activation. See text for detailed description and additional abbreviations.
