Table 1.
Cross tabulation of all analyzed patients and healthy volunteers by the number of csMVP-positive CTCs. The number 2.32 is the median number of csMVP-positive CTCs per milliliter (ml) in patients with HCC.
Disease groups | Case No. | No. of csMVP(+) CTC in blood | |
---|---|---|---|
Low (<2.32/ml) | High (≥2.32/ml) | ||
Non-neoplastic group* | (n = 12) | 12 (100%) | 0 (0%) |
Healthy control | (n = 10) | 10 (100%) | 0 (0%) |
Acute hepatitis | (n = 2) | 2 (100%) | 0 (0%) |
Primary HCC* | (n = 53) | 28 (52.8%) | 25 (47.2%) |
Secondary disease* | (n = 19) | 4 (21.1%) | 15 (78.9%) |
Recurrent HCC | (n = 5) | 1 (20%) | 4 (80%) |
Metastases to liver | (n = 14) | 3 (21.4%) | 11 (78.6%) |
* p < 0.001 by χ 2-test: non-neoplastic vs. primary HCC, p = 0.002; primary HCC vs. metastatic, p = 0.017; non-neoplastic vs. metastatic, p < 0.001 by χ2-test.