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. 2017 Oct 16;7:13242. doi: 10.1038/s41598-017-12829-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) PET/CT imaging 1 h post i.v. injection of ⁶⁸Ga-NRT-cFLFLF in 40-week-old ApoE⁻/⁻ mice. (b) PET/CT maximum intensity projection of the pulmonary region 1 h post i.v. injection of ⁶⁸Ga-NRT-cFLFLF in 40-week-old ApoE⁻/⁻ mice. (c) PET/CT imaging 1 h post i.v. injection of ⁶⁸Ga-NRT-cFLFLF in 16-week-old ApoE⁻/⁻ mice fed a high-fat diet (HFD). (d) PET/CT maximum intensity projection of pulmonary region 1 h post i.v. injection of ⁶⁸Ga-NRT-cFLFLF in 16-week-old ApoE⁻/⁻ mice fed a high-fat diet (HFD). (e) Organ biodistribution expressed as %ID/g in C57BL/6 mice, 40-week-old ApoE⁻/⁻ mice, and 16-week-old HFD ApoE⁻/⁻ mice. *P < 0.05, one-way ANOVA; error bars indicate s.d., N = 3.