Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 16;7:13222. doi: 10.1038/s41598-017-13471-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

HaESCs show abnormal cell cycle progression. (A) Growth rates of haESCs and diploid ESCs derived from AG-haESCs (AGH-OG-3; HG165). Data are shown as means ± sem. *P < 0.05, Haploid ESCs vs diploid ESCs at the same time point. (B) Cell cycle analyses of haploid and diploid ESCs derived from AG-haESCs (AGH-OG-3). Haploid (1N) and diploid (4N) cells were isolated simultaneously, and their cell cycle distributions were determined by flow cytometry. (C–E) Percentages of G0\G1-phase cells (C), S-phase cells (D), and G2\M-phase cells (E) in haploid and diploid ESCs derived from AG-haESCs (AGH-OG-3; HG165). Data are shown as means ± sem. ^**P < 0.01, ^***P < 0.001, Haploid ESCs vs diploid ESCs. (F and G) Time-lapse imaging of cell cycle-dependent fluorescence changes in diploid ESCs derived from HG165 haESCs (F), and in haploid HG165 ESCs (G). In this FUCCI system, cells in G1 phase shows orange, and cells in S, G2 and M phases shows green. Arrows indicate tracked cells.