Table 3. Logistic regression analysis of associations between TLR-9 rs187084 polymorphism and risk of osteoarthritis.
| Genotype | Cases* (n=215) | Controls* (n=215) | OR (95% CI) | P | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| TC vs. TT | 107/73 | 49.8/34.0 | 101/92 | 47.0/42.8 | 1.34 (0.89–2.01) | 0.167 |
| CC vs. TT | 28/73 | 13.0/34.0 | 18/92 | 8.4/42.8 | 1.96 (1.01–3.82) | 0.048 |
| CC vs. TC vs. TT | ||||||
| TC+CC vs. TT | 135/73 | 62.8/34.0 | 119/92 | 55.4/42.8 | 1.43 (0.96–2.12) | 0.075 |
| CC vs. TC + TT | 28/180 | 13.0/83.7 | 18/193 | 8.4/89.8 | 1.67 (0.89–3.12) | 0.109 |
| C vs. T | 163/253 | 37.9/58.8 | 137/285 | 31.9/66.3 | 1.34 (1.01–1.78) | 0.043 |
*
The genotyping was successful in 208 cases and 211 controls.
Bold values are statistically significant (P<0.05).