Table 4. Stratified analyses between TLR-9 rs187084 polymorphism and the risk of osteoarthritis.
Variable | TLR-9 rs187084 (case/control) | CC vs. TT | CC+TC vs. TT | CC vs. TC+TT | ||
---|---|---|---|---|---|---|
CC | TC | TT | ||||
Sex | ||||||
Male | 12/7 | 37/45 | 32/41 | 2.20 (0.78–6.23); 0.138 | 1.21 (0.66–2.21); 0.542 | 2.14 (0.80–5.72); 0.131 |
Female | 16/11 | 70/56 | 41/51 | 1.81 (0.76–4.32); 0.182 | 1.60 (0.95–2.69); 0.078 | 2.61 (1.08–6.33); 0.415 |
Age (years) | ||||||
<55 | 11/10 | 54/48 | 38/37 | 1.07 (0.41–2.82); 0.890 | 1.09 (0.61–1.94); 0.766 | 1.02 (0.41–2.51); 0.972 |
≥55 | 17/8 | 53/53 | 35/55 | 3.34 (1.30-8.56); 0.012 | 1.80 (1.05–3.11); 0.034 | 2.61 (1.08–6.33); 0.034 |
Bold values are statistically significant (P<0.05).