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. 2017 Oct 17;37(5):BSR20170995. doi: 10.1042/BSR20170995

Figure 2. Schematic representation of the subunit composition of dynein.

Figure 2

The motor containing cytoplasmic DHCs are shown in orange and associated intermediate and light chains in shades of blue. The motor domain is composed of six AAA ATPase domains arranged in a hexameric ring from which a MT binding stalk projects. The N-terminal tail of the heavy chain mediates its dimerization and contains the binding sites for two ICs and two LICs. The two ICs also interact with three pairs of light chains: Tctex, LC7 and LC8 (adapted from [24]).