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. 2017 Oct 17;37(5):BSR20170886. doi: 10.1042/BSR20170886

Figure 3. Effects of estrogen deprivation on cardiac remodeling protein expression in WT and GK rats (n = 6/group).

Figure 3

(A) Bax expression was increased in GKS and GKO rats. (B) Bcl-2 expression was no different between groups. (C and D) p38 phosphorylation and TGF-β expression were increased in GKS and GKO rats; *P<0.05 vs WTS, †P<0.05 vs WTO; GKO, Goto–Kakizaki rats with ovariectomy; GKS, Goto–Kakizaki with sham operation; TGF-β, transforming growth factor-β; WTO, wild-type rats with ovariectomy; WTS, wild-type with sham operation.