Figure 3.

Frequencies of haplotypes in HD disease and normal chromosomes. HD subjects carrying one expanded and one normal chromosome were included in this analysis to estimate overall frequencies of haplotypes. From haplotypes probabilistically determined based on a union set of 74 SNPs, we used our haplotype definitions to classify each chromosome. Subsequently, frequencies of our haplotypes in HD disease chromosomes (a) and normal chromosomes in HD subjects (b) were calculated and summarized.