TABLE 3.

Univariate Associations Between Patient Characteristics and Failure to Achieve Primary Fascial Closure

Factors	OR	95% CI	p
Age >65 y	0.64	0.32–1.29	0.210
Body mass index* >40 kg/m2	2.70	1.26–5.79	0.011
Charlson Comorbidity Index >4	1.69	0.60–4.75	0.316
ASA physical status classification >3	0.97	0.51–1.87	0.936
Abdominal sepsis*	3.06	1.51–6.19	0.002
Trauma**	0.30	0.14–0.64	0.002
Nontrauma hemorrhage/ACS	0.57	0.12–2.67	0.478
On admission
Heart rate >110 beats/min	0.59	0.28–1.23	0.159
Systolic blood pressure <90 mm Hg	2.06	0.71–5.94	0.183
Mean arterial pressure <60 mm Hg	1.65	0.40–6.84	0.487
Vasopressor infusion	0.98	0.45–2.14	0.952
Lactate >3.5 mmol/L	0.57	0.25–1.30	0.181
Creatinine >2.0 mg/dL	2.20	0.93–5.63	0.071
International normalized ratio >1.5	0.91	0.42–1.98	0.808
White blood cells >18 × 109/L	0.77	0.36–1.66	0.499
Initial laparotomy
Solid organ resection or repair**	0.37	0.15–0.93	0.034
Hollow viscous resection or repair	1.40	0.75–2.61	0.294
Washout/lysis of adhesions only	1.15	0.46–2.89	0.763
Transfusions during admission
>5 Red blood cell transfusion	1.27	0.69–2.33	0.439
>3 Plasma transfusions	1.38	0.75–2.54	0.301
Nadir serum albumin* <2.6 g/dL	3.15	1.27–7.82	0.013
Peak CRP* >250 mg/L	2.15	1.16–3.97	0.015

All 233 patients in the study population were included in this analysis. Optimal cutoff values for continuous variables were assessed by Youden index.¹⁶

^*Included in multivariable model.

^**Excluded from multivariable model because of colinearity to other variables in the regression equation.

ACS indicates abdominal compartment syndrome; ASA, American Society of Anesthesiologists.