Table 1.
Characteristics of cases and controls by factors matched (or surrogate factors) in the original study
| Variables | Controls | Cases | |
|---|---|---|---|
| CNS tumor | Leukemia | ||
| (N = 822) | (N = 72) | (N = 124) | |
| Year of birth | 1946–1989 | 1952–1989 | 1949–1989 |
| 1946–1959 | 120 (14.6%) | 11 (15.3%) | 22 (17.7%) |
| 1960–1969 | 240 (29.2%) | 16 (22.2%) | 44 (35.5%) |
| 1970–1979 | 294 (35.8%) | 28 (38.9%) | 35 (28.2%) |
| 1980–1989 | 168 (20.4%) | 17 (23.6%) | 23 (18.6%) |
| Age at diagnosis (years)a | |||
| Mean (SD) | 6.1 (4.4) | 5.6 (4.3) | 5.3 (4.1) |
| Min-Max | 0–15 | 0–14 | 0–14 |
| Sex | |||
| Male | 493 (60.0%) | 45 (62.5%) | 71 (57.3%) |
| Female | 329 (40.0%) | 27 (37.5%) | 53 (42.7%) |
| Ethnicity | |||
| Black | 18 (2.2%) | 3 (4.2%) | 2 (1.6%) |
| White | 804 (97.8%) | 69 (95.8%) | 122 (98.4%) |
| Maternal age (years) | |||
| Mean (SD) | 25.5 (5.4) | 25.2 (5.2) | 25.5 (5.8) |
| Min-Max | 14–44 | 15–37 | 16–42 |
| DOE sitesb | |||
| Hanford | 271 (32.9%) | 19 (26.4%) | 28 (22.6%) |
| INEL | 183 (22.3%) | 15 (20.8%) | 33 (26.6%) |
| Oak Ridge | 363 (44.2%) | 37 (51.4%) | 61 (49.2%) |
| Unknown | 5 (0.6%) | 1 (1.4%) | 2 (1.6%) |
| Gestational age (weeks)c | |||
| Mean (SD) | 39.3 (1.9) | 38.5 (2.4) | 39.4 (1.8) |
| Min-Max | 28–45 | 27–43 | 34–44 |
SD standard deviation, DOE Department of Energy
a Age at diagnosis for controls was calculated, using the year of diagnosis assigned by the original study, which was matched case-control study
b DOE sites: a surrogate variable for county of residence
c Not matched in the original study