Table 1.
Electrophysiological characterization of action potentials recorded from isolated cells.
| Action potentials (n = 41) | Interval (ms) | MDP (mV) | Peak (mV) | Amp (mV) | dV/dtmax (mV) | APD30 (ms) | APD40 (ms) | APD70 (ms) | APD80 (ms) | APD30-40/ APD70-80 |
|---|---|---|---|---|---|---|---|---|---|---|
| Central SAN-like (n = 21) | 400.0 ± 6.9 | –40.4 ± 4.2 | 7.3 ± 0.9 | 47.8 ± 3.5 | 1.0 ± 0.1 | 139.0 ± 9.7 | 162.3 ± 11.1 | 173.7 ± 11.9 | 196.3 ± 13.4 | 1.0 ± 0.1 |
| Atrial-like (n = 15) | 476.6 ± 22.3 | –77.2 ± 1.2 | 22.2 ± 1.3 | 99.4 ± 0.7 | 27.7 ± 1.1 | 77.4 ± 1.7 | 89.3 ± 2.0 | 107.2 ± 2.4 | 131.0 ± 2.9 | 1.1 ± 0.2 |
| Peripheral SAN-like (n = 5) | 406.4 ± 7.9 | –79.4 ± 22.2 | 27.5 ± 3.0 | 106.9 ± 2.2 | 4.9 ± 0.4 | 71.3 ± 3.5 | 83.7 ± 3.9 | 100.5 ± 4.7 | 112.1 ± 2.9 | 1.1 ± 0.1 |
Data are provided as means ± SEM
Amp amplitude, APD AP duration, dV/dt max maximal rate of depolarization, Interval beating rate interval, MDP maximum diastolic potential, Peak peak voltage, SAN sinoatrial node