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. 2017 Oct 16;8:230. doi: 10.1186/s13287-017-0675-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Structure of SIS-ECM seeded with CPCs for 1 week and response to β-adrenergic stimulation. a, b Cross-sectional images (HE staining) of SIS-ECM (a) and SIS-ECM seeded with CPCs after 1 week (b). c Contraction rate of SIS-ECM seeded with CPCs before and after the addition of 10 μM isoproterenol on day 8 of culture. Data expressed as mean ± SD. n = 5. *p < 0.05 vs basal state. SIS small intestinal submucosa