Table 5.
Clinical characteristics of the validation cohort.
| Variables | Cohort | Without CAD | With CAD | p value |
|---|---|---|---|---|
| n = 294 | n = 247 (84%) | n = 47 (16%) | ||
| Age | 56 (± 11) | 52 (± 10) | 66 (± 10) | < 0.001 |
| Male sex | 139 (47%) | 106 (43%) | 33 (70%) | 0.002 |
| Diabetes mellitus | 24 (8%) | 11 (4%) | 13 (28%) | < 0.001 |
| Arterial hypertension | 122 (41%) | 90 (36%) | 32 (68%) | < 0.001 |
| Dyslipidemia | 35 (12%) | 22 (9%) | 13 (28%) | 0.003 |
| Family history of CAD | 142 (48%) | 115 (46%) | 27 (57%) | 0.39 |
| Smoking | 145 (49%) | 116 (47%) | 29 (62%) | 0.18 |
| Chest pain | 125 (42,5%) | 85 (35%) | 39 (83%) | < 0.001 |
| Aortic valve repair | 104 (35%) | 61 (59%) | 43 (41%) | - |
| Mitral valve repair | 161 (55%) | 149 (93%) | 12 (7%) | - |
| Aortic and mitral valve repair | 29 (10%) | 25 (86%) | 4 (14%) | - |
Values expressed as mean ± SD or n (%). CAD: coronary artery disease. Differences with p value < 0.05 were considered statistically significant. T test was used for the variable 'age', and chi-square test, for the other variables.