Fig. 7.

Involvement of KCa3.1 in OGD-induced reactive astrogliosis. a, b Representative western blot showing GFAP expression in cultured astrocytes treated with OGD for 4 h in the presence of 1 μM TRAM-34 and 10 μM HC 067047. Quantification of western blot for GFAP expression (n = 3). Data are presented as means ± SEM. ^# p < 0.05 vs control, ^* p < 0.05 vs OGD alone. c, d Representative western blot and quantification of GFAP expression after 4 h OGD treatment in WT and KCa3.1 KCa3.1^−/− astrocytes (n = 3–4). ^*** p < 0.001, ^### p < 0.001. One-way ANOVA followed by the Dunnett’s multiple comparison test. Con control, WT wild type