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. Author manuscript; available in PMC: 2017 Oct 17.
Published in final edited form as: Biomaterials. 2016 Jul 26;104:361–371. doi: 10.1016/j.biomaterials.2016.07.029

Figure 3.

Figure 3

Experimental murine model of breast cancer lung metastasis and in vivo PET imaging with 64Cu-labeled GO conjugates. (a) Serial bioluminescence images and BLI signal intensity from the thoracic area of mice after intravenous injection of cbgLuc-MDA-MB-231 cells; (b) Serial coronal PET imaging of cbgLuc-MDA-MB-231 tumor-bearing mice at different time points post-injection of 64Cu-NOTA-GO-FSHR-mAb, 64Cu-NOTA-GO-FSHR-mAb with denature and 64Cu-NOTA-GO; (c) The cross-sectional slices of mice containing cbgLuc-MDA-MB-231 tumor nodules at 4 h post-injection of 64Cu-NOTA-GO-FSHR-mAb, 64Cu-NOTA-GO-FSHR-mAb with denature and 64Cu-NOTA-GO.