Table 1.

The ROI analysis of major organs from PET (unit: %ID/g)

Time Point	Tissue	64Cu-NOTA-GO-FSHR-mAb	64Cu-NOTA-GO-FSHR-mAb with denature	64Cu-NOTA-GO
0.5 h	Liver	16.5 ±4.0	20.4 ±1.2	18.8 ±5.0
	Tumor	10.6 ±1.1	2.9 ±0.2	3.8 ±0.4
	Blood	7.2 ±2.0	3.6 ±0.2	4.2 ±1.0
	Muscle	0.7 ±0.3	0.7 ±0.1	0.6 ±0.1
2 h	Liver	17.8± 1.2	19.3 ±1.5	20.8 ±3.0
	Tumor	10.6 ±1.0	2.8 ±0.4	3.1 ±0.5
	Blood	4.6 ±1.7	2.9 ±0.2	3.6 ±0.8
	Muscle	0.6 ±0.2	0.7 ±0.1	0.5 ±0.2
4 h	Liver	15.8± 2.5	14.3 ±4.5	19.1 ±2.8
	Tumor	11.6± 1.1	2.4 ±0.2	3.3 ±0.7
	Blood	4.5 ±0.5	3.6 ±0.8	3.3 ±0.7
	Muscle	0.6± 0.3	0.6 ±0.1	0.6 ±0.2
24 h	Liver	15.6± 1.9	13.6 ±2.5	17.5 ±2.9
	Tumor	9.3 ±0.9	2.5 ±0.2	1.9 ±0.4
	Blood	4.7± 1.1	4.2 ±1.0	1.4 ±0.1
	Muscle	0.6 ±0.2	0.6 ±0.02	0.6 ±0.1