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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Hum Pathol. 2017 Jul 11;66:144–151. doi: 10.1016/j.humpath.2017.06.014

Figure 2.

Figure 2

Four of the most common histological features trigger the differential diagnosis of CIN 2 and deployment of p16 IHC. A, Mitoses located in the middle level and/or atypical mitoses. B, Marked koilocytic atypia. C, Eroded or thin epithelium displaying abnormal nuclear features. D, Tangentially sectioned epithelium with substantial expansion of the basal and parabasal layers (H&E, original magnification ×200).