Table 1.
Baseline characteristics of study participants (mean ± SD)
| Baseline characteristics | Teriparatide (n = 6) | Placebo (n = 8) | P value |
|---|---|---|---|
| Age (years) | 32 ± 5.8 | 31 ± 3.4 | – |
| Weight (kg) | 57.4 ± 7.8 | 61.8 ± 13.2 | 0.75 |
| Height (cm) | 160.0 ± 3.6 | 160.4 ± 4.6 | 0.85 |
| Body mass index (kg/m2) | 22.4 ± 3.1 | 24.1 ± 4.9 | 0.7 |
| Alkaline phosphatase (U/L) | 58.3 ± 19.7 | 60.1 ± 26.3 | 0.95 |
| Serum P1NP (µg/L) | 40.1 ± 25.5 | 42.4 ± 11.9 | 0.33 |
| Serum OC (ng/mL) | 5.8 ± 5.0 | 7.9 ± 2.5 | 0.43 |
| Serum CTX (ng/mL) | 0.43 ± 0.2 | 0.54 ± 0.3 | 0.44 |
| Urine NTX/creatinine (nM/BCE) | 161.7 ± 132.1 | 356.9 ± 229.2 | 0.12 |
| Vitamin D | 31.8 ± 5.3 | 32.5 ± 8.9 | 0.75 |
| Calcium (urinary) | 8.6 ± 7.6 | 10.1 ± 5.7 | 0.56 |
| Calcium (serum) | 9.3 ± 0.4 | 9.5 ± 0.2 | 0.16 |
| Parathyroid hormone (PTH) | 28.3 ± 4.6 | 26.6 ± 9.1 | 0.33 |
| DXA spine (Z-score) | −1.2 ± 0.7 | −0.7 ± 1.3 | 0.4 |
| DXA left femoral neck (Z-score) | −0.7 ± 1.0 | −0.8 ± 1.5 | 0.94 |
| DXA right femoral neck (Z-score) | −0.6 ± 1.0 | −0.27 ±1.1 | 0.55 |
| DXA left total hip (Z-score) | −0.6 ± 0.7 | −0.26 ± 1.2 | 0.58 |
| DXA right total hip (Z-score) | −0.5 ± 0.8 | −0.09 ± 1.1 | 0.43 |
| DXA whole body (Z-score) | −0.4 ± 0.7 | 0.46 ± 1.0 | 0.12 |