Table 6.

Annotation agreement between student and expert annotator

Class	Entity	Precision	Recall	F-measure
Nanomedicine description	Company	0.96	0.46	0.62
	FDA approval date	0.97	1	0.98
	Trade name	0.99	1	1
	US patent	1	1	1
Physicochemical characterization	Active ingredient	0.89	0.79	0.84
	Molecular weight	0.89	0.69	0.78
	Nanoparticle	0.64	0.42	0.51
	Particle diameter	1	0.71	0.83
	Surface coating	0.48	0.27	0.34
Pharmacokinetic parameters	AUC	0.82	0.47	0.60
	Clearance	0.74	0.65	0.69
	Cmax	0.91	0.63	0.74
	Elimination half-life	0.80	0.73	0.76
	Plasma half-life	1	0.75	0.86
	Tmax	0.91	0.56	0.69
	Volume of distribution	0.91	0.87	0.89
Exposure	Dose	0.86	0.32	0.46
	Route of administration	0.95	0.49	0.65
Biologic response	Adverse reaction	0.96	0.06	0.11
	Indication	0.98	0.53	0.69
Total		0.95	0.55	0.69

Abbreviations: AUC, area under the curve; Cmax, maximum concentration measured in blood; FDA, US Food and Drug Administration; Tmax, time to reach Cmax.