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In vitro cytotoxicity of blank (without loading drug) PLGA NPs and PLGA-Glc NPs in Hep-2 cells. Cell viability (%) was measured by 3-(4,5-dimethylthiazol-2-yl)-5(3-carboxymethonyphenol)-2-(4-sulfophenyl)-2H-tetrazolium assay after applying various concentrations of blank NPs (~1,000 μg/mL) for (A) 24 hours, (B) 48 hours, and (C) 72 hours. Data are expressed as the mean ± SD (n=4).
Abbreviations: NPs, nanoparticles; Glc, star glucose; PLGA, poly((D,L)lactic-glycolic)acid.
