Table 1.

Particle characterizations of DCT-loaded PLGA NPs and PLGA-Glc NPs

Composition	Mean diameter (nm)	Polydispersity index	Zeta potential (mV)	Encapsulation efficiency (%)	Drug content (%)
DCT/PLGA NPs	256±4	0.07±0.03	−18.58±1.93	53.57±2.97	4.87±0.27
DCT/PLGA-Glc NPs	241±5	0.07±0.02	−16.70±1.31	52.03±1.42	4.73±0.13

Notes: Data are presented as the mean ± SD (n≥3).

$$\text{Encapsulation}\text{efficiency}(\%)=\frac{\text{Actual}\text{amount}\text{of}\text{DCT}\text{in}\text{NPs}}{\text{Input}\text{amount}\text{of}\text{DCT}\text{in}\text{NPs}}\times 100;\text{Drug}\text{content(\%)=}\frac{\text{Actual}\text{amount}\text{of}\text{DCT}\text{in}\text{NPs}}{\text{Amount}\text{of}\text{DCT}-\text{loaded}\text{NPs}}\times 100$$

Abbreviations: DCT, docetaxel; Glc, star glucose; NPs, nanoparticles; PLGA, poly((D,L)lactic-glycolic)acid.