Table 1.
Serum susceptibility pattern of different borrelial species to human and animal sera.
| Species a | B. burgdorferi | B. afzelii | B. bavariensis | B. garinii | B. valaisiana | B. lusitaniae | B. japonica | B. bissettii | B. andersonii |
|---|---|---|---|---|---|---|---|---|---|
| Human | R | R | R | S | S | S | R | I | S |
| Mouse | R | R | R | S | S | ND | R | R | ND |
| Rat | S | R | R | S | ND | ND | ND | ND | ND |
| Hamster | R | R | R | S | S | S | R | ND | ND |
| Squirrel | R | R | R | S | S | ND | R | ND | ND |
| Cat | I | R | R | I | R | ND | R | ND | ND |
| Dog | I | R | R | S/I | I | S | I | R | R |
| Mouflon | I | R | R | R/I | R | R | R | R | I |
| Lynx | I | I | R | I | R | S | S | R | I |
| Wolf | I | S | R | S/I | S | S | S | R | I |
| Sheep | I | S | S | S | S | R | R | S/R | I |
| Horse | I | S | S | S | S | S | S | ND | ND |
| Pig | I | S | S | S | S | S | S | ND | ND |
| Rabbit | I | S | ND | S | ND | ND | ND | I | ND |
| Pheasant | I | S | S | R | R | S | S | ND | ND |
| Blackbird | I | S | S | R | R | S | S | ND | ND |
| Goat | S | S | ND | S | ND | ND | ND | ND | ND |
| Bovine | S | S | S | S | S | S | S | S | S |
| Deer | S | S | S | S | S | S | S | S | S |
| Eur. Bison | S | S | S | S | S | S | S | S | S |
| Lizard | S | S | S | R | R | R | S | S | ND |
| Quail | R | ND | ND | ND | ND | ND | ND | S | ND |
a variations in the serum susceptibility patterns have been reported for the polymorphic genospecies B. garinii [46]. B. spielmanii has not been included due to the lack of available data but this genospecies resists complement-mediated killing by human serum [65]; Light blue, serum-resistant (R); grey, intermediate serum-resistant (I); yellow, serum-sensitive (S), transparent, no data available (ND); orange, phenotype unclear.