Table 2.
Binding of human and animal factor H to different borrelial species.
| Species | B. burgdorferi | B. afzelii | B. bavariensis | B. garinii | B. valaisiana | B. lusitaniae | B. japonica | B. bissettii | B. andersonii |
|---|---|---|---|---|---|---|---|---|---|
| Human | + | + | − | − | − | − | (+) | (+) | + |
| Mouse | (+) | + | (+) | − | − | − | + | + | + |
| Rat | − | − | − | − | − | − | + | − | − |
| Cat | − | + | − | − | − | − | + | − | − |
| Dog | − | − | − | − | + | − | + | − | − |
| Sheep | + | − | − | − | − | − | − | + | − |
| Horse | (+) | − | − | − | − | − | − | − | − |
| Cattle | − | − | − | − | − | − | − | − | − |
Symbols in parenthesis indicate controversial results of Factor H binding to the respective borrelial species. In each case, further studies are required to unambiguously determine whether those species indeed interact with factor H.