Table 1.

Clinical details of affected LHON carriers.

Patient	Onset (Yrs)a	Smokerb	Visual recoveryc	Visual acuityd
				RE	LE
LHON-A	21	No	No	HM	CF
LHON-B	18	No	Yes	20/30	CF
LHON-C	45	Yes	No	CF	CF
LHON-D	18	No	No	HM	HM

CF = counting fingers; HM = hand movements; LE = left eye; RE = right eye; Yrs = years.

^aAge of onset of visual loss.

^bSmoking status prior to disease onset.

^cSpontaneous visual recovery with none of the patients having been treated with quinone analogues following disease onset.

^dBest-corrected visual acuity at the last clinic visit, which was at a similar level at the nadir except for the right eye of patient LHON-B.