Table 2.

Genotyping information of three SNPs in Chinese children

SNP	Nearest gene	Chr.	Position	Allele (1/2)a	EAFb	EAFc	EAFd	Call rate, %	FST	ALIR Study		CPOOA Study		SCICO Study
										genotype e	HWE p valuef	genotype	HWE p value	genotype	HWE p value
rs564343	PACS1	11	65651742	A/G	0.72	0.69	0.41	99.9	0.096	72/61/18	0.366	233/178/44	0.246	809/640/132	0.732
rs11109072	RMST	12	96425401	A/C	0.26	0.23	0.03	99.9	0.107	9/62/80	0.505	32/172/251	0.733	105/635/843	0.319
rs1957893	PRKCH	14	60977864	T/C	0.33	0.29	0.08	99.9	0.115	20/69/62	0.907	58/187/210	0.111	185/654/742	0.028

ALIR = Adolescent Lipids, Insulin Resistance and Candidate Genes; Chr. = chromosome; EAF = effect allele frequency; CPOOA = Comprehensive Prevention Project for Overweight and Obese Adolescents; Position = NCBI build 36.3 (NCBI, Bethesda, MD); SCICO = School-Based Comprehensive Intervention on Childhood Obesity; SNP = single nucleotide polymorphism.

^a1 = effect allele, 2 = other allele.

^bEffect allele frequency in all genotyped individuals of the present study.

^cEffect allele frequency reported in the HapMap Han Chinese, and that of rs11109072 is from HapMap database among Chinese and Japanese individuals (CHB+JPT).

^dEffect allele frequency of SNPs in the original study, and that of the proxy SNP (rs1957893) is from NCBI database among the same populations that in the discovery study.

^eGenotypes of normal weight group (11/12/22).

^fHWE p value in normal-weight Chinese children.